The gas chromatograph-mass spectrometer is the earliest developed chromatography-mass spectrometer instrument. Since the sample separated from the gas chromatograph is in a gaseous state and the mobile phase is gas, it matches the sampling requirements of the mass spectrometer. It is easiest to combine these two instruments. Combined use. The gas chromatography mass spectrometer combines the advantages of gas chromatography and mass spectrometry, making up for their respective shortcomings. It has the characteristics of high sensitivity, fast analysis speed and strong identification ability. It can complete the separation and identification of the components to be measured at the same time. It can be used Qualitative and quantitative analysis of unknown components in multi-component mixtures, determine the molecular structure of compounds, accurately determine the molecular weight of compounds, perform trace analysis of drugs and metabolites in biological samples and body fluids, and directly characterize volatile components And quantitative analysis, non-volatile components and thermally unstable substances can be appropriately derivatized and analyzed. Gas chromatography mass spectrometry has been widely used in doping detection, prescription research, pharmacokinetic research, etc., and its application scope is becoming more and more extensive.
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